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Acne conglobata is a highly inflammatory disease presenting with comedones, nodules, , and draining sinus tracts. (2025). 9780071380768, McGraw-Hill. ISBN 9780071380768 (2025). 9781416029991, Mosby. ISBN 9781416029991
This condition generally begins between the ages of 18 and 30. It usually persists for a very long time, and often until the patient is around 40 years old. Although it often occurs where there is already an active acne problem, it can also happen to people whose acne has subsided. Although the cause of this type of acne is unknown, it is associated with testosterone and thus appears mainly in males. It can be caused by anabolic steroid abuse and sometimes appears in males after stopping testosterone therapy. It can also happen to someone who has a tumor that is releasing large amounts of androgens, or to people in remission from diseases, such as leukemia. In certain persons, the condition may be triggered by exposure to aromatic hydrocarbons or ingestion of halogens.
Surgery may be necessary to remove large nodules. Alternatively, nodules can be injected with such as triamcinolone.
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